Genomics provides insights into gene expression during development (temporal and spatial) that can be used to dissect mechanisms of regeneration and the differentiation of stem cells. Our laboratory is leading efforts in the new Institute for Genomic Biology in an innovative interdisciplinary approach to harvesting gene expression information to create design rules for stem cell biology, regenerative medicine and tissue engineering. These investigations include utilization of laser capture microscopy, construction of microfluidic devices and the development of comparative phenomics to dissect regeneration using the mouse, pig and planeria models.
Extramural funding from the U.S.D.A. Competitive Grants Program, the NIH, private agencies, industry, and special grants support our laboratory.