The goal of the project is to understand the architecture of chromosomes during meiosis by:

1. Imaging the synaptonemal complex (Sycp) in the wild-type and mutant spermatocytes. 

2. Imaging recombination nodule components.

The image on the left shows the localization of single fluorophores for the two homologous chromosome labeled with Sycp3-Flux640 and Sycp1-Flux680. The image on the right is the ratiometrically-separated fluorophores, which shows sycp1 (red) localized between the two homologs labeled with sycp3 (red). The microscope used is the Abberior Minflux and the image is  generated using the imspector software.